Picked up playing the guitar in high school. He played with his first band 'Pegasus' doing mainly covers of bands like the Allman Brothers, Heart & Wishbone Ash. Ehsaan joined the band Crosswinds in 1982 playing alongside fellow guitarist Sanjay Divecha.
He attended the 'Musicians Institute' then known as the 'Guitar Institute of Technology' in Hollywood California from 1985 to 1986 learning from players like Danny Gilbert, Robben Ford, Steve Trovato and Keith Wyatt.
In 1986 Ehsaan came back to India and almost immediately began playing sessions mainly for TV commercials and film scores. At the same time he started playing in a band called “Mickeys New Home“along with Ranjit Barot & Sanjay Divecha. He soon began composing music independently for commercials in 1989 and it is during this period that Ehsaan met up with Shankar and Loy.
Ehsaan collaborated with his close friends Loy Mendonsa & Shankar Mahadevan and in 1996 Shankar Ehsaan Loy was formed. Together the trio have composed music for several films - Dus, Dil Chahta Hai, Kal Ho Na Ho, Rock On, Bunty aur Bubli, Jhoom Barabar Jhoom, Kabhi Alvida Na Kehna, My Name is Khan, Taare Zameen Par, Bhag Milkha Bhag, 2 States, etc... They have had over 75 Number 1 songs spanning across their career.They have gone on to win the National Award for Excellence in Music for the soundtrack of Kal Ho Na Ho, Screen, Filmfare & IIFA awards for the music of Dil Chahta Hai, Kal Ho Na Ho, Bunty Aur Babli, My Name is Khan, Bhag Milkha Bhag, Mirzya, Rock On, Taare Zameen Par.
Amongst their body of work SEL have also composed the song for the closing of the Commonwealth Games, ICC Cricket World Cup sing in 2011 in addition to performing at both ceremonies. They have also composed several TV serial title tracks - Kya Hum Paachvi Pass Se Tez Hai?, Rang Badalti Odhni & Aarambh.
Currently he is a Judge for the reality show the Stage now shooting Season 3 on Colours Infinity and is also busy working on several sound tracks for their upcoming films.